Xilio Therapeutics, Inc. is a clinical-stage biotechnology company focused on discovering and developing tumor-activated immuno-oncology therapies designed to enhance anti-cancer immune responses. The company's pipeline includes vilastobart, a tumor-activated, Fc-enhanced anti-CTLA-4 antibody being evaluated in combination with atezolizumab for advanced solid tumors and microsatellite stable metastatic colorectal cancer, and efarindodekin alfa, a tumor-activated IL-12 molecule in clinical trials for advanced solid tumors. Xilio is also advancing XTX501, a bispecific PD-1/masked IL-2 molecule, and multiple masked T cell engager programs targeting tumor-associated antigens including PSMA, CLDN18.2, and STEAP1. The company's masked immunotherapy platform aims to selectively activate immune responses within the tumor microenvironment while minimizing systemic side effects. Xilio maintains strategic collaborations with major pharmaceutical partners, including an agreement with AbbVie to develop novel tumor-activated antibody-based immunotherapies, and generates collaboration revenue to extend its development runway.
Website828 Winter Street
Waltham, MA, 02451
United States
Dr. Houvras brings over two decades of executive leadership across premier industry and academic research institutions in clinical development, translational medicine and immuno-oncologyWALTHAM, Mass., Sept. 28, 2026 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing masked immuno-oncology therapies for people living with cancer, today announced the appointment of Dr. Yariv Houvras as chief medical officer. “We are thrill
WALTHAM, Mass., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing masked immuno-oncology therapies for people living with cancer, today announced that, effective September 1, 2026, the company granted non-qualified stock options to purchase 19,865 shares of its common stock to two new employees under Xilio Therapeutics’ 2022 Inducement Stock Incentive Plan. The stock options have an exercise price of $8.88
Received FDA clearance of IND application for XTX501, a potential best-in-class bispecific PD-1 / masked IL-2 Advancing IND-enabling studies for potential first-in-class multi-specific, masked T cell engager programs targeting CLDN18.2 and PSMA+STEAP1; IND applications anticipated in the second half of 2027 Cash runway into the first quarter of 2028 expected to support key milestones across pipeline of next generation multi-specific I-O therapies WALTHAM, Mass., Aug. 12, 2026 (GLOBE NEWSWIRE) --
WALTHAM, Mass., July 06, 2026 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing masked immuno-oncology therapies for people living with cancer, today announced that, effective July 1, 2026, the company granted non-qualified stock options to purchase 107,060 shares of its common stock to three new employees under Xilio Therapeutics’ 2022 Inducement Stock Incentive Plan. The stock options have an exercise price of $9.22 pe
Investors talking about XLO also mention
What share of all stock conversation is about XLO?
| 1 Day1D | 1 Week1W | 1 Month1M | 1 Year1Y | 50-Day MAclick to plot | 200-Day MAclick to plot | |
|---|---|---|---|---|---|---|
| Attention | 0% 0 | 0% new | 0% 0 | 0% 0 |
Of the messages about XLO that take a side, what share is each?
| 1 Day1D | 1 Week1W | 1 Month1M | 1 Year1Y | 50-Day MAclick to plot | 200-Day MAclick to plot | |
|---|---|---|---|---|---|---|
| Bullish | — | 100% | 100% 0 | 82.81% -3.55 | ||
| Bearish | — | 0% | 0% 0 | 17.19% +3.55 |
Of the messages about XLO that carry a topic, what share is each?
| 1 Day1D | 1 Week1W | 1 Month1M | 1 Year1Y | 50-Day MAclick to plot | 200-Day MAclick to plot | |
|---|---|---|---|---|---|---|
| Announcements | — | — | — | 79.14% | ||
| Technical Analysis | — | — | — | 18.72% | ||
| Analysts | — | — | — | 0.53% | ||
| Controversies | — | — | — | 0% | ||
| Earnings | — | — | — | 1.6% | ||
| Macro | — | — | — | 0% |
Of the messages about XLO, what share comes from each group?
| 1 Day1D | 1 Week1W | 1 Month1M | 1 Year1Y | 50-Day MAclick to plot | 200-Day MAclick to plot | |
|---|---|---|---|---|---|---|
| Regulars | — | 100% | 100% | 39.55% | ||
| Newcomers | — | 0% | 0% | 60.45% |